Stochastic and proliferative events initiated from a single cell can disrupt homeostatic balance and lead to fatal disease processes such as cancer metastasis.To overcome metastasis, it is necessary to detect and quantify sparsely distributed metastatic cells throughout the body at early stages.Here, we demonstrate that clear, unobstructed brain/bo
The development of entrepreneurial interest among young people represents an important Chips alternative in terms of using the potential of young people.Youth unemployment represents a significant loss of human capital that could contribute to economic growth.The last challenges that young people faced (mass emigration abroad, general demographic d
Abstract Background The dietary methylamines choline, carnitine, and phosphatidylcholine are used by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA).However, little is known about the use of trimethylamine N-oxide (TMAO) by this consortium of microbes.Results A feeding study using deuterated TMAO in C57BL6/J mic
Single-molecule and bulk biophysical approaches to study protein-DNA interactions on surface-immobilized nucleic acid templates typically rely on modifying the ends of linear DNA molecules to enable surface-DNA attachments.Unless both strands are constrained, this results in topologically free DNA molecules and the inability to observe supercoiling
Miniaturizing flow cytometry requires a comprehensive approach to redesigning the conventional fluidic and optical systems to have a small footprint and simple usage and to enable rapid cell analysis.Microfluidic methods have addressed some challenges in limiting the realization of microflow cytometry, but most microfluidics-based flow cytometry te